FIGURE 6.

ApoE3 and reelin do not affect cellular ATP content and ABCG1 and SR-B1 mRNA levels. A, mouse macrophages were treated with 2 μg/ml reelin or 3 μg/ml apoE3 for time periods as indicated. Cellular ATP levels were determined by luminescence assay. B, mouse macrophages were incubated with 3 μg/ml apoE3, 2 μg/ml reelin, or culture medium alone (Control) for 1 h. The mRNA levels of ABCG1 and SR-B1 were determined by quantitative real-time RT-PCR and normalized to GAPDH mRNA. Values represent the mean ± S.E. of three independent experiments.