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Comparison of active site residues in related AdoCbl-dependent mutases. The MCM structure from Propionibacterium shermanii (Protein Data Bank code 4REQ) was used as a template to show that Tyr and Arg in MCM/ECM correspond to Phe and Gln in ICM/IcmF. In HCM, this pair of residues is Ile and Gln.
