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. 2011 Dec 12;287(6):4177–4187. doi: 10.1074/jbc.M111.296434

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© 2012 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 10. — Akt and caspase 3 are activated in OLs in vivo. Confocal micrographs show immunofluorescent co-localization using the OL-specific antibody anti-RIP (A and D) in combination with antibodies generated against phosphorylated Akt (Ser-473) (B, MCAO sham-operated vehicle treated rat) or activated caspase 3 (E, MCAO vehicle-treated rat) in the external capsule. Merged images demonstrate expression of phosphorylated Akt (C) and activated caspase 3 (F) in RIP-positive OLs. Arrows denote immunoreactivity. Scale bars = 50 μm.