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Examples of granules in mast cell cytoplasmic extensions. (A) The granule (G) is isolated from the mast cell cytoplasm by several layers of filopodia (*, first layer; arrow, multiple layers). The cell in B is in the pia and electron-dense granules (white asterisk) are frequently present in the small cellular extensions. This mast cell is primarily filled with electron-lucent granules associated with piecemeal degranulation (G). MC, mast cell; nu, nucleus.
