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. 2012 Jan 12;11:4. doi: 10.1186/1476-4598-11-4

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Copyright ©2012 Barta et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Analysis of lung inflammation. (A) Total and lineage-specific leukocyte numbers in bronchoalveolar lavage fluid (BALF) one day after the last NTHi or saline aerosol exposure are shown (n = 4, mean ± SE, *= P < 0.05 for NTHi or NNK/NTHi-exposed Gprc5a-/- mice vs PBS or NNK-exposed Gprc5a-/- mice). (B) Histologic grading of inflammation in lung tissue from each treatment group (n = 6, mean ± SE, *= P < 0.05 for NNK vs PBS, **= P < 0.05 for NTHi vs NNK, and ***= P < 0.05 for NNK/NTHi-exposed Gprc5a-/- mice vs NTHi-exposed Gprc5a-/- mice).