Table 3.
Genotype | n | TC (mmol/L) |
TG (mmol/L) |
HDL-C (mmol/L) |
LDL-C (mmol/L) |
ApoA1 (g/L) |
ApoB (g/L) |
ApoA1/ ApoB |
---|---|---|---|---|---|---|---|---|
Mulao | ||||||||
AA | 155 | 5.13 ± 1.07 | 1.10(0.75) | 1.80 ± 0.54 | 3.05 ± 0.88 | 1.34 ± 0.43 | 1.00 ± 0.61 | 1.61 ± 0.85 |
AG | 348 | 5.05 ± 1.28 | 1.04(0.79) | 1.75 ± 0.44 | 2.93 ± 0.91 | 1.35 ± 0.39 | 0.96 ± 0.49 | 1.60 ± 0.63 |
GG | 136 | 5.02 ± 1.82 | 1.09(0.90) | 1.71 ± 0.41 | 2.84 ± 0.93 | 1.27 ± 0.43 | 0.94 ± 0.49 | 1.54 ± 0.71 |
F | - | 0.283 | 1.492 | 2.316 | 1.882 | 2.073 | 0.450 | 0.396 |
P | - | 0.754 | 0.474 | 0.099 | 0.153 | 0.127 | 0.638 | 0.673 |
AA | 155 | 5.13 ± 1.07 | 1.10(0.75) | 1.82 ± 0.54 | 3.05 ± 0.88 | 1.34 ± 0.43 | 1.00 ± 0.61 | 1.61 ± 0.85 |
AG/GG | 484 | 5.05 ± 1.44 | 1.05(0.80) | 1.74 ± 0.43 | 2.91 ± 0.92 | 1.33 ± 0.40 | 0.96 ± 0.49 | 1.58 ± 0.65 |
F | - | 0.410 | -0.904 | 3.700 | 2.754 | 0.052 | 0.754 | 0.208 |
P | - | 0.522 | 0.366 | 0.055 | 0.097 | 0.819 | 0.385 | 0.648 |
Male | ||||||||
AA | 80 | 5.13 ± 0.86 | 1.09(1.20) | 1.84 ± 0.63 | 2.99 ± 0.69 | 1.37 ± 0.44 | 1.04 ± 0.67 | 1.59 ± 0.80 |
AG | 155 | 5.22 ± 1.30 | 1.19(1.11) | 1.76 ± 0.45 | 2.91 ± 0.87 | 1.39 ± 0.39 | 0.98 ± 0.49 | 1.58 ± 0.59 |
GG | 66 | 5.11 ± 2.30 | 1.29(1.12) | 1.63 ± 0.40a | 2.75 ± 0.97 | 1.28 ± 0.48 | 1.03 ± 0.61 | 1.45 ± 0.68 |
F | - | 0.154 | 3.403 | 3.652 | 1.510 | 1.577 | 0.358 | 1.017 |
P | - | 0.858 | 0.182 | 0.027 | 0.223 | 0.208 | 0.700 | 0.363 |
Female | ||||||||
AA | 75 | 5.14 ± 1.26 | 1.19(0.72) | 1.79 ± 0.42 | 3.09 ± 1.05 | 1.30 ± 0.41 | 0.96 ± 0.51 | 1.62 ± 0.90 |
AG | 193 | 4.92 ± 1.25 | 1.00(0.64) | 1.74 ± 0.44 | 2.96 ± 0.95 | 1.32 ± 0.38 | 0.94 ± 0.50 | 1.62 ± 0.66 |
GG | 70 | 4.93 ± 1.17 | 1.03(0.60) | 1.77 ± 0.41 | 2.91 ± 0.88 | 1.25 ± 0.39 | 0.86 ± 0.35 | 1.63 ± 0.73 |
F | - | 0.954 | 2.297 | 0.325 | 0.686 | 0.714 | 1.006 | 0.005 |
P | - | 0.386 | 0.317 | 0.723 | 0.505 | 0.491 | 0.367 | 0.995 |
Han | ||||||||
AA | 185 | 4.97 ± 1.18 | 1.23(1.07) | 1.63 ± 0.41 | 2.79 ± 0.85 | 1.32 ± 0.25 | 0.86 ± 0.18 | 1.62 ± 0.54 |
AG | 312 | 5.11 ± 1.10 | 1.08(1.01) | 1.78 ± 0.65a | 3.00 ± 0.87a | 1.35 ± 0.25 | 0.87 ± 0.21 | 1.63 ± 0.46 |
GG | 147 | 5.10 ± 1.11 | 1.00(0.70) | 1.73 ± 0.48 | 2.95 ± 0.96 | 1.33 ± 0.31 | 0.88 ± 0.24 | 1.61 ± 0.55 |
F | - | 0.926 | 6.130 | 4.275 | 3.359 | 0.975 | 0.458 | 0.112 |
P | - | 0.397 | 0.047 | 0.014 | 0.035 | 0.378 | 0.633 | 0.894 |
AA | 185 | 4.99 ± 1.18 | 1.23(1.06) | 1.64 ± 0.41 | 2.79 ± 0.85 | 1.33 ± 0.25 | 0.86 ± 0.18 | 1.62 ± 0.54 |
AG/GG | 459 | 5.10 ± 1.10 | 1.05(0.95) | 1.76 ± 0.60 | 2.98 ± 0.90 | 1.34 ± 0.27 | 0.87 ± 0.22 | 1.62 ± 0.49 |
F | - | 1.403 | -1.756 | 6.598 | 6.749 | 0.609 | 0.507 | 0.002 |
P | - | 0.237 | 0.079 | 0.010 | 0.010 | 0.435 | 0.477 | 0.963 |
Male | ||||||||
AA | 73 | 4.98 ± 1.29 | 1.30(0.93) | 1.53 ± 0.38 | 2.62 ± 0.75 | 1.27 ± 0.26 | 0.88 ± 0.19 | 1.49 ± 0.47 |
AG | 160 | 5.35 ± 1.12a | 1.30(1.10) | 1.69 ± 0.40a | 3.14 ± 0.83a | 1.37 ± 0.27a | 0.94 ± 0.21 | 1.53 ± 0.42 |
GG | 66 | 5.41 ± 1.05a | 1.15(1.16) | 1.74 ± 0.47a | 3.14 ± 0.90a | 1.41 ± 0.33a | 0.97 ± 0.24a | 1.52 ± 0.49 |
F | - | 3.178 | 0.329 | 5.594 | 10.859 | 5.919 | 3.302 | 0.234 |
P | - | 0.043 | 0.848 | 0.004 | 0.000 | 0.003 | 0.038 | 0.791 |
Female | ||||||||
AA | 112 | 4.94 ± 1.10 | 1.15(1.09) | 1.72 ± 0.41 | 2.89 ± 0.90 | 1.35 ± 0.25 | 0.83 ± 0.17 | 1.72 ± 0.56 |
AG | 152 | 4.87 ± 1.04 | 0.97(0.81) | 1.85 ± 0.83 | 2.84 ± 0.89 | 1.33 ± 0.24 | 0.82 ± 0.20 | 1.72 ± 0.47 |
GG | 81 | 4.86 ± 1.09 | 0.95(0.60) | 1.72 ± 0.49 | 2.82 ± 0.98 | 1.28 ± 0.29 | 0.80 ± 0.21 | 1.68 ± 0.59 |
F | - | 0.199 | 4.704 | 2.020 | 0.190 | 1.903 | 0.461 | 0.171 |
P | - | 0.820 | 0.095 | 0.134 | 0.827 | 0.151 | 0.631 | 0.843 |
TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B. The values of triglyceride were presented as median (interquartile range). The difference among the genotypes was determined by the Kruskal-Wallis test or the Wilcoxon-Mann-Whitney test. aP < 0.05 comparison with AA genotype of the same ethnic group.