Skip to main content
. 2012 Feb 17;7(2):e29613. doi: 10.1371/journal.pone.0029613

Figure 2. Association rates under the holdout approach using a second data set to test reproducibility.

Figure 2

Results for 100 simulations of Inline graphic family trios as a function of the recombination rate using the recessive and one-locus genetic model and haplotypes of lengths Inline graphic (left plot), Inline graphic (plot in the middle) and Inline graphic (right plot). A nominal level of Inline graphic and a relative risk of Inline graphic were used for all plots. Results for Inline graphic Inline graphic Inline graphic and Inline graphic i.e. all tests were applied under the holdout approach, are plotted in purple circles, blue triangles, green squares and red diamonds respectively. Dashed lines show results for a data subset of Inline graphic trios randomly chosen while solid lines show results for a second data subset of Inline graphic trios used to test reproducibility of the holdout approach.