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. 2012 Feb 17;7(2):e29613. doi: 10.1371/journal.pone.0029613

Table 3. Genotype counts and their transmissions used by Inline graphic.

Nontransmitted Nontransmitted
haplotype haplotype
Transmitted Inline graphic Inline graphic Transmitted Inline graphic Inline graphic
haplotype AB Ab aB ab Total haplotype AB Ab aB ab Total
Inline graphic AB Inline graphic 30 3 7 40 Inline graphic AB Inline graphic 24 5 5 34
Inline graphic Ab 37 Inline graphic 6 5 48 Inline graphic Ab 31 Inline graphic Inline graphic Inline graphic 31
aB 8 6 Inline graphic 3 17 aB 9 Inline graphic Inline graphic Inline graphic 9
ab 11 3 1 Inline graphic 15 ab 11 Inline graphic Inline graphic Inline graphic 11
Total 56 39 10 15 121 Total 51 24 5 5 85

Haplotypes in rows represent those transmitted haplotypes at each genotype. Haplotypes in columns represent those nontransmitted haplotypes at each genotype. Homozygous genotype counts (diagonal) are crossed off the tables as they are not used to compute Inline graphic Left grid: genotype counts from the training data set (see Table 2) used to make up groups Inline graphic and Inline graphic in Inline graphic Groups are: Inline graphic with those haplotypes with Inline graphic counts larger than Inline graphic counts (Ab: Inline graphic versus Inline graphic and aB: Inline graphic versus Inline graphic) and Inline graphic with Inline graphic counts larger than Inline graphic counts (Inline graphic versus Inline graphic). Right grid: genotype counts from the test data set used to compute the statistic. As the length similarity measure is used to assign an haplotype to a group, and the two most similar haplotypes to haplotype Inline graphic belongs to group Inline graphic Inline graphic is assigned to Inline graphic All the haplotypes belonging to the same group are considered of having an equivalent effect and are collapsed. Therefore, parental genotypes in the test data set with haplotypes belonging to the same group are considered as homozygous and not used by Inline graphic (they are crossed off the table too).