Figure 8. DRE triggers pro-death autophagy in MV-4-11 cells but not in non-cancerous Peripheral blood mononuclear cells (ncPBMCs).

MV-4-11 cells were treated with DRE for 48 hours and analyzed for the induction of autophagy; Tamoxifen (TAM) was used as a positive control for the induction of pro-surivival autophagy. Following treatment, the cells were stained with MDC to detect autophagic vacuoles and counterstained with PI to detect cell death. Fluorescence images were captured. Magnification: 400×.