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. 2012 Feb 17;7(2):e30881. doi: 10.1371/journal.pone.0030881

Figure 1. Plasma CXCL9, CXCL10, sIL-2R, and sCD14 represent a biomarker cluster that distinguishes HIV subjects from healthy uninfected controls.

Figure 1

(A) Hierarchical clustering (supervised only by sample) by Euclidean distance and average linkage of 17 plasma biomarkers in 57 HIV patients and 29 healthy uninfected controls shows increased plasma levels and clustering of CXCL9, CXCL10, sIL-2R, and sCD14 (highlighted in box) in HIV subjects compared to healthy controls. In heat maps, red and blue represent increased and decreased levels relative to the mean level of a biomarker, respectively. Each column and row defines individual patient and biomarkers, respectively.