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. 2012 Feb 17;7(2):e31299. doi: 10.1371/journal.pone.0031299

Figure 2. Vaccinia vaccinated mice display greater lung T cell numbers and enhanced function following bleomycin challenge.

Figure 2

A. Total lung cell numbers of vaccinia vaccinated and mock (PBS) vaccinated mice following bleomycin administration. B. Total CD4+ and CD8+ T cells present in the lung following bleomycin administration. C. Flow cytometric analysis of percentages of lung CD4+ and CD8+ T cells. D. Total lung CD4+ IFNγ+ and CD8+ IFNγ+ T cells following bleomycin administration. E. ELISA analysis of IFNγ concentration in bronchial lavage fluid following bleomycin administration. F. Total lung CD4+ IL17+ T cells following bleomycin administration. Error bars indicate one standard deviation of the mean and (*) indicates statistical significance (p<.05) between groups. All experiments were performed at least three times, at least 10 animals per group per experiment.