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| Toxicity | Number of episodes | Number of patients | |
|---|---|---|---|
| Grade III | 24 | 10 | |
| Absolute neutrophil count (>500-1000 G/L) | 6 | 4 | |
| Hemoglobin (6.5–8.0 g/dL) | 4 | 3 | |
| Leukocytes (1,000–2,000 G/L) | 7 | 5 | |
| Neuropathy | 1 | 1 | |
| Mucositis | 1 | 1 | |
| Renal Insuffisiency | 1 | 1 | |
| Platelets (10.000-50.000 G/L) | 3 | 2 | |
| Grade IV | 4 | ||
| Absolute neutrophil count (>500-1000 G/L) | 2 | 1 | |
| Platelets < 10.000 G/L | 2 | 2 |
