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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Biol Psychiatry. 2011 Dec 14;71(5):392–402. doi: 10.1016/j.biopsych.2011.09.034

Figure 3. Large de novo copy number variants (CNV) in Tourette syndrome (TS) subjects.

Figure 3

Plots of relative microarray probe Log R Ratios (LRR) and B Allele Frequencies (BAF) in unaffected father, TS proband, and unaffected mother. CNV regions are bounded by horizontal lines in LRR and BAF plots, outlined in red on chromosome ideograms, and represented by green (duplication) or red (deletion) below chromosome bands. Data is shown for (A) a 51.8 Mb heterozygous duplication on chromosome 5 (chr5: 127,500,000-179,295,570), containing 447 RefSeq transcripts; (B) a 1.2 Mb region on chromosome 20p13 (chr20: 2,758,098-3,942,609), containing 27 RefSeq transcripts; and (C) a 2.5 Mb region on chromosome 22q11.21 (chr22:17,269,490-19,792,353), containing 56 RefSeq transcripts. All de novo deletions were confirmed by qPCR.