Fig. 1.
Comparison of brain cells apoptosis in normal, opium addicted, diabetic and opium diabetic-addicted Wistar rats. Data are from 7 animals is presented in each group. In male rats: aSignificant difference between normal, opium-addicted diabetic and opium-addicted non-diabetic (p<0.001 and p<0.001 respectively). bSignificant difference between non-addicted diabetic and opium-addicted diabetic groups (p<0.001). cSignificant difference between opium-addicted non-diabetic and non-addicted diabetic groups (p<0.001). In female rats: dSignificant differences between normal, opium-addicted diabetic and opium-addicted non-diabetic groups (p<0.001 and p<0.001 respectively). eSignificant difference between opium-addicted and non-addicted diabetic groups (p <0.001). fSignificant difference between non-addicted diabetic and opium-addicted diabetic groups (p<0.001). Sex associated: gSignificant difference between opium-addicted male and female (p< 0.001). hSignificant difference between non-addict diabetics male and non-addict diabetics female (p=0.006). iSignificant difference between opium-addicted diabetic males and opium-addicted diabetic females (p<0.001).