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. 2011 Dec 27;15(6):339–344. doi: 10.4196/kjpp.2011.15.6.339

Fig. 2.

Fig. 2

Vasorelaxing effects of an ethanol extract from Ulmus davidiana var. japonica (UD) in rat aortic rings. (A) Typical tracing of the vasorelaxing effect of UD on endothelium-intact rings. UD evoked vasorelaxation in phenylephrine (300 nM) or high K+ (60 mM)-preconstricted aortic rings. Pretreatment with 0.1 mM L-nitroarginine methyl ester (L-NAME) abrogated UD-induced vasorelaxation. (B) Summarized data for the vasorelaxing effect of UD on phenylephrine-induced contraction. (C) Summarized data for the vasorelaxing effect of UD on high K+ (60 mM)-induced contraction. Vehicle: In endothelium intact rings with DMSO as a vehicle. Intact Endothelium: In endothelium intact rings. Intact endotheium+L-NAME: In endothelium-intact rings pretreated with L-NAME. Rubbed endothelium: In endothelium rubbed rings. Contraction is represented as % contraction of each maximal contraction. Data are the mean±S.E. *p<0.05 versus vehicle.