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Agonists of mouse and human Toll-like receptors
| TLR | Ligand |
|---|---|
| 1/2 | Triacyl lipopeptides |
| 2/6 | Diacyl lipopeptides |
| 3 | dsRNA |
| 4 | Lipopolysaccharide |
| 5 | Flagellin |
| 7 | ssRNA |
| 8 | ssRNA in humans; unclear in mice |
| 9 | CpG DNA, malarial hemozoin |
| 10a | Unknown |
| 11b | Uropathogenic bacteria, Toxoplasma gondii profilin-like protein |
| 12b | Unknown |
| 13b | Unknown |
aExpressed only in humans.
bExpressed only in mice.
