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. 2012 Feb 20;3:59. doi: 10.3389/fmicb.2012.00059

Figure 1.

Figure 1

Putative motifs within the KSHV ORF57 protein. KSHV ORF57 is a 455 amino acid protein with an exon junction within the codon for aa 17. The functional motifs comprise a putative CKII phosphorylation site (region 18–43); three nuclear localization signals (NLS1,2,3; regions 101–107, 121–131, 143–152); an A/T hook (region 119–131); two arginine–glycine–glycine motifs (RGG1,2; regions 138–140, 372–374); a leucine zipper (region 343–364); a zinc finger domain (region 423–432); and a hydrophobic glycine–leucine–phenylalanine–phenylalanine motif (GLFF; region 448–451). The putative phosphorylation sites were predicted using GPS V2.1 (Xue et al., 2008).