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. Author manuscript; available in PMC: 2012 Feb 20.
Published in final edited form as: Neurogastroenterol Motil. 2011 May 24;23(8):801–e339. doi: 10.1111/j.1365-2982.2011.01728.x

Figure 6.

Figure 6

Sympathetic sprouting during and post colonic inflammation. Intracolonic instillation of vehicle (50% EtOH) did not induce colonic inflammation (A), while intracolonic instillation of tri-nitrobenzene sulfonic acid (TNBS) induced colonic inflammation with the most severe case at 3 days (B) and gradually recovered at 7 days (C) and beyond (D). The relative damage score (E) showed a robust colonic inflammation at 3 days and then back toward normal level at 21 days post TNBS treatment. The extent of the sympathetic sprouting in thoracolumbar DRGs was persistently increased from 3 days to 21 days post colitis induction (F). The increases in TH levels in the DRG at 21 days of colitis were confirmed with Western blot analysis (G). Bar = 250 μm. *P < 0.05.