Figure 2.

Algorithm based on pharmacodynamic concepts.

Notes: *Contraindicated in patient with history of stroke and TIA. **High-dose clopidogrel option; 600 mg loading and 150 mg daily, guided by platelet function assay. ***Diabetes mellitus, left main stenosis, diffuse atherosclerotic disease, chronic renal failure, and acute coronary syndromes.

Abbreviations: TIA, transient ischemic attack; ACS, acute coronary syndromes; PCI, percutaneous coronary intervention; DM, diabetes mellitus; LM, left main; CAD, coronary artery disease.