Table 2.
Impact of MACC1 SNP rs1990172 on overall survival, shown for dominant, recessive, and additive genetic models of inheritance
| Genetic model | Adjustment model | HR | 95%CI | P-value |
|---|---|---|---|---|
| Additive | Model 1 | 1.38 | 1.05-1.82 | 0.023 |
| Model 2 | 1.49 | 1.12-1.98 | 0.007 | |
| Dominant | Model 1 | 1.59 | 1.05-2.40 | 0.028 |
| Model 2 | 1.63 | 1.08-2.47 | 0.020 | |
| Recessive | Model 1 | 1.50 | 0.86-2.60 | 0.152 |
| Model 2 | 1.82 | 1.04-3.18 | 0.036 |
Hazard ratios (HR) and 95% confidence intervals (95% CI) were obtained from univariate Cox regression analysis (model 1) and multivariate Cox regression analysis adjusting for age and UICC stage (model 2)