Table 1.
Characteristics on admission of K. pneumoniae infected patients compared to patients with H. influenzae/S pneumoniae ALRI aged ≥5 years in univariate analysis
| Patients with K. pneumoniae ALRI (n = 43) |
Patients with H. influenzae and S. pneumoniae ALRI (n = 160) |
P-value | |
|---|---|---|---|
| Age, median years (Inter Quartile Range [IQR]) | 55 (45-72) | 57 (42-65) | 0.8 |
| Male gender (%) | 14 (32.6) | 80 (50.0) | 0.04 |
| Co-morbidities (%) | |||
| Smoking history | 10 (23.3) | 50 (31.2) | 0.3 |
| Cardiovascular disease | 6 (13.9) | 17 (10.6) | 0.5 |
| Diabetes mellitus | 7 (16.3) | 10 (6.2) | 0.03 |
| Alcoholism | 6 (13.9) | 35 (21.9) | 0.2 |
| Renal impairment | 3 (7.0) | 10 (6.2) | 0.8 |
| Liver disease | 1 (2.3) | 1 (0.6) | 0.3 |
| Prior treatment | 19 (44.2) | 92 (57.5) | 0.08 |
| Prior antibiotic | 5 (11.6) | 7 (4.4) | 0.08 |
| Clinical data | |||
| Chest pain | 24 (55.8) | 106 (66.2) | 0.1 |
| Hemoptysis | 10 (23.2) | 23 (14.4) | 0.1 |
| Severity criteria | 5 (11.6) | 8 (5.0) | 0.1 |
| Laboratory results | |||
| Leucocytes, median 109/L (IQR) | 8.5 (6.7 - 10.8) | 8.3 (6.2 - 10.6) | 0.6 |
| AST*, median U/L (IQR) | 29 (25-42) | 27.5 (21-38) | 0.1 |
| ALT*, median U/L (IQR) | 30 (21-32) | 26 (20-34) | 0.4 |
| Blood creatinine μmol/L (IQR) | 88.4 (77.8 - 108.7) | 88.4 (76.0 - 99.0) | 0.6 |
NOTE. Liver enzymes: AST (Aspartate transaminase) and ALT (Alanine transaminase)