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Clinical score evolution (A) and body weight variations (B) in experimental animals (control female: white triangle, control male: white circle, EAE female: black triangle, EAE male: black circle). Significant differences were observed in the clinical disability score between male and female animals (two-way ANOVA, gender effect, **p = 0.0028, F(1,649) = 9.027; days post-immunization (DPI) effect, *** p < 0.0001, F(27,649) = 54.32.
