Figure 6. Cholesterol efflux capacity of HDL fractions from ApoF KO mice.

Serum was collected from wild type and ApoF KO mice for the measurement of cholesterol efflux capacity.. Apo B lipoproteins were precipitated with polyethylene glycol, and the resulting supernatant (containing HDL and other soluble serum proteins) was tested for its ability to promote cholesterol efflux as described in the methods section. A. ABCG1-mediated cholesterol efflux to apo B-depleted serum from wild type (WT) and ApoF knockout (KO) mice. B. ABCA1-mediated cholesterol efflux.