Table 2. Blood Chemistry Parameters in ApoF KO mice.
Females | Males | Reference Intervals for Mouse Blood | |||
WT (n = 4) | KO (n = 5) | WT (n = 12) | KO (n = 6) | ||
Sodium (mmol/L) | 143+/−0.9 | 141+/−1.1 | 152+/−13 | 142+/−1.4 | 124–174 |
Potassium (mmol/L) | 5.8+/−0.8 | 5.5+/−0.5 | 5.6+/−0.7 | 5.2+/−0.2 | 4.6–8 |
Creatinine (mg/dl) | 0.2+/−0.0 | 0.2+/−0.0 | 0.2+/−0.0 | 0.2+/−0.0 | 0.2–0.8 |
BUN (mg/dl) | 28+/−2.2 | 28+/−3.0 | 30+/−4.5 | 32+/−4.5 | 18–29 |
AST (U/L) | 85+/−22 | 100+/−64 | 103+/−81 | 68+/−17 | 59–247 |
ALT (U/L) | 46+/−6 | 60+/−11 | 51+/−12 | 45+/−7 | 28–132 |
Blood was collected in Lithium-Heparin tubes and used to measure classical chemistry parameters. Sodium, Potassium, Creatinine, Blood Urea Nitrogen (BUN), Aspartate Aminotransferase (AST), and Alanine Aminotransferase (ALT) were measured on a clinical chemistry analyzer. Data is reported as the mean +/− standard deviation. A two-tailed t-test was used to compare between genotypes by sex, and no statistically significant differences were found.