Table 4. The effect of cholesterol loading and depletion on plasma lipids in ApoF KO mice.

	0.01% Ezetimibe		0.2% Cholesterol
	WT	KO	WT	KO
“n”	6	6	4	5
Total Cholesterol (mg/dl)	70+/−6	77+/−9	79+/−10	86+/−14
HDL Cholesterol (mg/dl)	45+/−4	49+/−4	45+/−4	49+/−5
Non HDL Cholesterol (mg/dl)	25+/−3	28+/−7	34+/−6	37+/−10
Triglycerides (mg/dl)	38+/−6	30+/−4 *	23+/−4	24+/−5
Body Weight (g)	18.4+/−0.6	19.3+/−0.9	19.4+/−1.8	20.2+/−0.8
Liver Weight (g)	0.96+/−0.5	0.97+/−0.10	1.11+/−0.12	1.05+/−0.07
Liver : BW (%)	5.2+/−0.1	5.0+/−0.3	5.8+/−0.9	5.2+/−0.4
Liver Cholesterol (mg/g)	3.2+/−0.7	3.8+/−0.4	3.9+/−0.4	4.8+/−0.6

ApoF wild type (WT) and knockout (KO) mice (9–10 weeks of age) were fed a chow diet supplemented with either 0.01% ezetimibe or 0.2% cholesterol for 11 days. Values are reported as mean +/− standard deviation.

^*P<0.05 relative to WT for each treatment group.