Table 3. A summary of prionogenic (Amyloid Prion Type Am) and candidate-prionogenic sequences in the PrionHome database from Saccharomyces cerevisiae, that have N/Q and F/Y compositional biases.

PrionHome Classification	# of sequences that have N/Q bias, but no F/Y bias	# of sequences that have N/Q bias, and F/Y bias*
Prionogenic**	19	6***
Candidate-Prionogenic ****	329	48
Candidate-Prionogenic experimentally shown not to form amyloid*****	16	2

*F/Y compositional biases with binomial P-values< = 10⁻⁶ are considered (see Database Construction & Content for details).

**This data includes the Alberti, et al. (2009) data from screens for candidate prionogenic sequences.

***As an example, the SQL query to obtain this data is: SELECT prion_id , name FROM main WHERE prion_type LIKE’%prionogenic%’ AND bias REGEXP ‘Y|F’ AND bias REGEXP ‘N|Q’ AND organism LIKE ‘%cerevisiae%’.

****Polymorphic sequences have been removed from these totals. This is the total list of Prion-Like sequences from Harrison, et al. (2006) and Alberti, et al. (2009).

*****Prion-like sequences that failed to form amyloid by any tests in Alberti, et al. (2009).