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. 2012 Feb 20;7(2):e31528. doi: 10.1371/journal.pone.0031528

Figure 8. Changes in PTC specificity by engineering the 230-loop.

Figure 8

Putrescine (circles) or ornithine (squares) concentration dependency of enzyme activity for wild type PTC (WT, open symbols) and for the engineered form in which the 230YGLY233 sequence was replaced by VSMG (Engineered, closed symbols). WT activity is plotted in the left y-axis whereas other activities are plotted on the right y-axis. Inset: zoom on the engineered form with putrescine.