Table 1. Characteristics of the studies included in this meta-analysis.
First author | Year | Country | Ethnicity | Genotyping methods | Sample size (case/control) | Case (%) | Control (%) | P HWE | ||||
GG | GC | CC | GG | GC | CC | |||||||
Hu | 2008 | China | Asian | PCR-RFLP | 1009/1093 | 165(16.4) | 515(51.0) | 329(32.6) | 180(16.5) | 551(50.4) | 362(33.1) | 0.221 |
Hoffman | 2009 | USA | Mix | MassARRAY | 439/478 | 234(53.3) | 176(40.1) | 29(6.6) | 273(57.1) | 178(37.2) | 27(5.6) | 0.775 |
Pastrello | 2010 | Italy | European | Sequencing | 88/155 | 53(60.2) | 30(34.1) | 5(5.7) | 90(58.1) | 59(38.1) | 6(3.9) | 0.332 |
Catucci | 2010 | Italy | European | PCR-RFLP | 754/1243 | 409(54.2) | 286(37.9) | 59(7.8) | 650(52.3) | 520(41.8) | 73(5.9) | 0.019 |
Catucci | 2010 | Germany | European | PCR-RFLP | 805/904 | 451(56.0) | 304(37.8) | 50(6.2) | 536(59.3) | 318(35.2) | 50(5.5) | 0.753 |
Garcia | 2011 | France | European | Taqman | 1130/596 | 676(59.8) | 388(34.3) | 66(5.8) | 352(59.1) | 220(36.9) | 24(4.0) | 0.150 |
PCR-RFLP: Polymerase Chain Reaction-restriction Fragment Length Polymorphism; HWE: Hardy-Weinberg Equilibrium.