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. 2012 Feb 20;7(2):e31615. doi: 10.1371/journal.pone.0031615

Table 1. Characteristics of the studies included in this meta-analysis.

First author Year Country Ethnicity Genotyping methods Sample size (case/control) Case (%) Control (%) P HWE
GG GC CC GG GC CC
Hu 2008 China Asian PCR-RFLP 1009/1093 165(16.4) 515(51.0) 329(32.6) 180(16.5) 551(50.4) 362(33.1) 0.221
Hoffman 2009 USA Mix MassARRAY 439/478 234(53.3) 176(40.1) 29(6.6) 273(57.1) 178(37.2) 27(5.6) 0.775
Pastrello 2010 Italy European Sequencing 88/155 53(60.2) 30(34.1) 5(5.7) 90(58.1) 59(38.1) 6(3.9) 0.332
Catucci 2010 Italy European PCR-RFLP 754/1243 409(54.2) 286(37.9) 59(7.8) 650(52.3) 520(41.8) 73(5.9) 0.019
Catucci 2010 Germany European PCR-RFLP 805/904 451(56.0) 304(37.8) 50(6.2) 536(59.3) 318(35.2) 50(5.5) 0.753
Garcia 2011 France European Taqman 1130/596 676(59.8) 388(34.3) 66(5.8) 352(59.1) 220(36.9) 24(4.0) 0.150

PCR-RFLP: Polymerase Chain Reaction-restriction Fragment Length Polymorphism; HWE: Hardy-Weinberg Equilibrium.