Table 2.
Sensitivity and specificity of PCR test compared to culture / AFB smear
| Test | Test results | OATB control groups | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | |
|---|---|---|---|---|---|---|---|
| (N = 80) | (N = 25) | ||||||
| Multiplex PCR | Positive | 66 | - | ||||
| Negative | 14 | 25 | 82.5 | 100 | 100 | 64.1 | |
| MPB64 | Positive | 64 | - | ||||
| Negative | 16 | 25 | 80 | 100 | 100 | 60.97 | |
| IS6110 | Positive | 59 | - | ||||
| Negative | 21 | 25 | 73.75 | 100 | 100 | 54.34 | |
| Culture | Positive | 3 | - | ||||
| Negative | 77 | 25 | 3.89 | 100 | 100 | 27.17 | |
| Microscopy | Positive | 1 | - | ||||
| Negative | 79 | 25 | 1.25 | 100 | 100 | 24.03 | |
AFB acid fast bacilli, OATB osteoarticular tuberculosis, PCR polymerase chain reaction, PPV positive predictive value, NPV negative predictive value