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. 2012 Jan 4;36(2):245–254. doi: 10.1007/s00264-011-1432-2

Table 4.

Risk factors for severe disease at time of diagnosis (n = 161)

Nonsevere (%) Severe (%) Crude OR (95% CI) Adjusted OR (95% CI)
Overall 107 (66) 54 (34)
Site
 Guru Teg Bahadur hospitala 24 (48) 26 (52) 1.00 (ref)
 VIMHANS hospitala 83 (75) 28 (25) 0.31 (0.15–0.62) ***
State of residence
 Delhi 56 (64) 32 (36) 1.00 (ref) 1.00 (ref)
 Haryana 8 (89) 1 (11) 0.22 (0.01–1.27) * 0.20 (0.01–1.53)
 Uttar Pradesh 35 (71) 14 (29) 0.70 (0.32–1.47) 1.02 (0.37–2.77)
 Other 8 (53) 7 (47) 1.53 (0.49–4.66) 4.33 (1.06–18.93) **
Sex
 Female 54 (68) 26 (33) 1.00 (ref)
 Male 53 (65) 28 (35) 1.10 (0.57–2.12)
Age
 ≤ 30 42 (55) 34 (45) 1.00 (ref) 1.00 (ref)
 ≥ 31 65 (76) 20 (24) 0.38 (0.20–0.74) *** 0.32 (0.13–0.76) ***
Religion
 Hindu 83 (65) 44 (35) 1.00 (ref) 1.00 (ref)
 Muslim 9 (50) 9 (50) 1.89 (0.69–5.17) 0.71 (0.20–2.43)
 Other 15 (94) 1 (6) 0.13 (0.01–0.65) ** 0.01 (0.01–0.65) **
Educational statusb
 Low 19 (48) 21 (53) 1.00 (ref) 1.00 (ref)
 Medium 32 (64) 18 (36) 0.51 (0.22–1.18) * 0.41 (0.14–1.14)
 High 56 (79) 15 (21) 0.24 (0.10–0.56) *** 0.20 (0.06–0.62) ***
Monthly incomeb
 Lowa 31 (50) 31 (50) 1.00 (ref)
 Mediuma 26 (72) 10 (28) 0.38 (0.15–0.91) **
 Higha 47 (82) 10 (18) 0.21 (0.09–0.48) ***
 Unknowna 3 (50) 3 (50) 1.00 (0.17–5.77)
Current professionb
 Unemployed 13 (59) 9 (41) 1.00 (ref)
 Normal unemployed 37 (70) 16 (30) 0.62 (0.22–1.78)
 Student 16 (57) 12 (43) 1.08 (0.35–3.41)
 Semi skilled 17 (68) 8 (32) 0.68 (0.20–2.25)
 Professional 24 (73) 9 (27) 0.54 (0.17–1.70)
Tobacco use
 Current or past 20 (71) 8 (29) 1.00 (ref)
 Never 87 (65) 46 (35) 1.32 (0.56–3.40)
Alcohol use
 Current or pasta 22 (79) 6 (21) 1.00 (ref)
 Nevera 85 (64) 48 (36) 2.07 (0.83–5.94) *
Health insurance
 No 78 (64) 44 (36) 1.00 (ref)
 Yes 29 (74) 10 (26) 0.61 (0.26–1.34)
General healthcare center
 Government 24 (57) 18 (43) 1.00 (ref) 1.00 (ref)
 Private 73 (69) 33 (31) 0.60 (0.29–1.27) * 0.46 (0.15–1.30)
 Other 10 (77) 3 (23) 0.40 (0.08–1.53) * 0.17 (0.03–0.87) **
Cost for general healthcare visit (rupees)
 <50a 36 (71) 15 (29) 1.00 (ref)
 <50–100a 18 (56) 14 (44) 1.87 (0.74–4.74) *
 <200a 16 (67) 8 (33) 1.20 (0.41–3.37)
 <300a 16 (67) 8 (33) 1.20 (0.41–3.37)
 >300a 21 (70) 9 (30) 1.03 (0.37–2.73)
Delay in diagnosis
 <9 months 85 (70) 36 (30) 1.00 (ref) 1.00 (ref)
 >10 months 22 (55) 18 (45) 1.93 (0.92–4.03) * 2.67 (1.05–6.99) **
First health center
 Government 37 (65) 20 (35) 1.00 (ref)
 Private 57 (63) 34 (37) 1.10 (0.56–2.22)
 Other 13 (100) 0 (0) 0.00
Time to general healthcare center
 <30 mina 104 (68) 48 (32) 1.00 (ref)
 >30 mina 3 (33) 6 (67) 4.33 (1.10–21.22) **
Distance to general healthcare center
 1 km 55 (64) 31 (36) 1.00 (ref) 1.00 (ref)
 2–3 km 38 (85) 7 (16) 0.33 (0.12–0.78) ** 0.48 (0.16–1.36)
 >4 km 14 (47) 16 (53) 2.03 (0.88–4.76) * 2.44 (0.79–7.80)

a Variable was included in the backwards stepwise multivariate logistic regression model but eliminated

b See appendix B for definitions of education, income, and profession

* p < 0.20

** p < 0.05

*** p < 0.01