Table 4.

Estimated Least-Squares Mean Telomere Length (z-score) and 95% Confidence Interval by Moderate or Vigorous Physical Activity Reported in 1988, Nurses’ Health Study, United States

	Moderate- or Vigorous-Intensity Activity, hours/weeka										Ptrendb
	<1 (n = 3,775)		1–<2 (n = 1,161)		2–<4 (n = 1,269)		4–<7 (n = 823)		≥7 (n = 660)
	LTL	95% CI	LTL	95% CI	LTL	95% CI	LTL	95% CI	LTL	95% CI
Age adjusted	−0.02	−0.05, 0.009	−0.007	−0.06, 0.05	0.08	0.03, 0.13	0.05	−0.02, 0.12	0.007	−0.07, 0.08	0.02
Multivariatec	−0.005	−0.06, 0.05	0.01	−0.06, 0.09	0.10	0.03, 0.18	0.07	−0.01, 0.16	0.03	−0.06, 0.13	0.02
Multivariate + body mass indexd,e	−0.004	−0.06, 0.06	0.01	−0.06, 0.09	0.10	0.02, 0.17	0.07	−0.02, 0.16	0.03	−0.07, 0.12	0.05

Abbreviations: CI, confidence interval; LTL, leukocyte telomere length.

^aIncludes brisk walking, jogging, running, biking, swimming, tennis, and calisthenics or aerobics.

^bP values are 2 sided.

^cAdjusted for age in years (continuous), pack-years of smoking (0, >0−<20, 20−<40, ≥40, missing), menopausal status (pre-, post-, dubious), postmenopausal hormone use (never, past, current <5 years, current ≥5 years, missing), case status (case, control), easy walking (0, >0–<1, 1–<2.5, ≥2.5 hours/week).

^dBody mass index at blood collection (continuous).

^eBody mass index: weight (kg)/height (m)².