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. 2012 Feb 3;175(5):368–375. doi: 10.1093/aje/kwr433

Table 2.

Estimated Odds Ratios for Incident AIDS According to Human Immunodeficiency Virus Viral Load Set Point, Multicenter AIDS Cohort Study, 1984–1998a

Method Estimate of β1 SE or SDb OR = exp(β1) 95% CI or 95% PIc
Maximum likelihood 1.072 0.308d 2.92 1.60, 5.34e
Bayesianf
    MCMCg 0.905 0.285 2.47 1.41, 4.32
0.905 2.47 1.42, 4.32
    Rejection samplingg 0.908 0.288 2.48 1.41, 4.36
0.900 2.46 1.41, 4.42
    Data augmentationh 0.901 0.283 2.46 1.41, 4.29

Abbreviations: AIDS, acquired immunodeficiency syndrome; CI, confidence interval; MCMC, Markov chain Monte Carlo; OR, odds ratio; PI, posterior interval; SD, standard deviation; SE, standard error.

a

Data were obtained from the Multicenter AIDS Cohort Study (13). Results were adjusted for age and race.

b

Standard deviation unless otherwise specified.

c

95% posterior interval unless otherwise specified.

d

Standard error.

e

95% confidence interval.

f

All Bayesian methods used a lognormal odds-ratio prior with 95% limits of 1/4 and 4.

g

First estimate of β1 is the mean of 20,000 draws or 6,718 rejection-sampling draws; first limits are exp(mean ± 1.96 × SD), where the mean and SD are computed from the draws. Second estimate is the median; second limits are the 2.5th and 97.5th percentiles. The simulation error was 0.0006 for MCMC and 0.0033 for rejection sampling.

h

Estimate is the posterior mode (maximum of posterior); limits are exp(mean ± 1.96 × SD), where the SD is the β1 diagonal entry from the inverse of the total (i.e., data and prior) information matrix.