Table 2.
Estimated Odds Ratios for Incident AIDS According to Human Immunodeficiency Virus Viral Load Set Point, Multicenter AIDS Cohort Study, 1984–1998a
| Method | Estimate of β1 | SE or SDb | OR = exp(β1) | 95% CI or 95% PIc |
| Maximum likelihood | 1.072 | 0.308d | 2.92 | 1.60, 5.34e |
| Bayesianf | ||||
| MCMCg | 0.905 | 0.285 | 2.47 | 1.41, 4.32 |
| 0.905 | 2.47 | 1.42, 4.32 | ||
| Rejection samplingg | 0.908 | 0.288 | 2.48 | 1.41, 4.36 |
| 0.900 | 2.46 | 1.41, 4.42 | ||
| Data augmentationh | 0.901 | 0.283 | 2.46 | 1.41, 4.29 |
Abbreviations: AIDS, acquired immunodeficiency syndrome; CI, confidence interval; MCMC, Markov chain Monte Carlo; OR, odds ratio; PI, posterior interval; SD, standard deviation; SE, standard error.
Data were obtained from the Multicenter AIDS Cohort Study (13). Results were adjusted for age and race.
Standard deviation unless otherwise specified.
95% posterior interval unless otherwise specified.
Standard error.
95% confidence interval.
All Bayesian methods used a lognormal odds-ratio prior with 95% limits of 1/4 and 4.
First estimate of β1 is the mean of 20,000 draws or 6,718 rejection-sampling draws; first limits are exp(mean ± 1.96 × SD), where the mean and SD are computed from the draws. Second estimate is the median; second limits are the 2.5th and 97.5th percentiles. The simulation error was 0.0006 for MCMC and 0.0033 for rejection sampling.
Estimate is the posterior mode (maximum of posterior); limits are exp(mean ± 1.96 × SD), where the SD is the β1 diagonal entry from the inverse of the total (i.e., data and prior) information matrix.