Table 1.

Details of patients and biopsy findings of Parkinson disease patients

No.		Age	Sex	Hallmarks of clinical diagnosis			Flexion angle (°)	Biopsy site	Biopsy findings
									Major findings			Minor findings
	No. in (14).			Duration of PD in years	Duration of camptocormia in months	Therapy: l-Dopa, mg/d/other			Structural defects	Acid phosphatase activity in muscle fibers	Myofibrillar structural defects	Caliber variation	Whorled fibers	Endomysial fibrosis	Nuclear bags	Increase in internalized nuclei	Fiber type I:II
B1	1	55	F	4	8	800/–	30	Lumbar	+	+	+	+	+	+	+	+	10:1
B2	2	59	F	10	28	700/–	90	Th12	+	+	n.e.	+	0	+	+	+	10:1
B3	13	72	M	17	30	600/–	80	Lumbar	+	+	+	+	+	+	+	+	3:1
B4	5	64	M	7	32	1,400/–	60	Thoraco-lumbar	+	+	Ø	+	0	+	+	+	1:1.5
B5	8	68	F	22	5	–/DBS	70	Th12–L1	+	+	+	+	0	+	+	+	10:1
B6	11	69	M	15	12	300/–	60	L3	+	+	+	+	+	+	+	+	20:1
B8	4	62	M	10	5	800/–	30	L1	+	+	+	+	+	+	+	+	20:1
B9	10	68	F	41	54	500/DBS	90	Not specified	+	+	+	+	+	+	+	+	40:1
B10	6	66	F	11	36	800/–	45	Th12–L1	n.e.	n.e.	+	+	+	+	+	0	n.e.
B11	9	68	M	9	72	1,350/–	70	Cervical	+	+	+	+	+	+	+	0	1:1
B12	7	67	M	10	17	850/–	45	Th10–12	+	+	+	+	0	+	+	+	1:1
B13	3	61	F	13	17	1,200/–	90	Th12–L1	+	+	Ø	+	+	+	+	+	5:1
B14	–	70	M	6	9	750/–	30–40	Not specified	+	+	+	+	+	+	+	+	40:1

+ Biopsy findings detectable, 0 not detectable, n.e. not exploitable, Ø no material available for electron microscopy, DBS deep brain stimulation