Table 1.
Immature | Mature | Mature activity-dependent down regulation | |
---|---|---|---|
Thr906 and Thr1006 | Phosphorylated by Wnk kinases (Rinehart et al., 2009) | Dephosphorylated (Rinehart et al., 2009) | ? |
Tyr1087 | Dephosphorylated (Vale et al., 2005) | Phosphorylated (Vale et al., 2005; Wake et al., 2007; Watanabe et al., 2009) | Phosphorylation/Dephosphorylation of Tyr903 Tyr1087 (Wake et al., 2007; Lee et al., 2010) |
Ser940 | ? | Phosphorylated by PKC (Lee et al., 2007) | Dephosphorylated by PP1 (Lee et al., 2011) |