Figure 1. Detection of tumor-specific mutated DNA in the margin surrounding a colorectal cancer liver metastasis.

Punch biopsies were obtained at 4 mm distances from the macroscopically visual tumor margin. Shown below are flow cytometric data from BEAMing reactions of a sample at 4 mm that was macroscopically normal appearing but with detectable mutant DNA (left) and a sample at 8 mm distance from the same lesion that did not show presence of mutated tumor DNA (right).