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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Clin Cancer Res. 2011 Apr 29;17(11):3551–3557. doi: 10.1158/1078-0432.CCR-10-3087

Table 1.

Patient Characteristics and Molecular Margin Status.

Patient No. Age Gender Chemotherapy Response Gene Exon Mutation Ray Fraction mutated:wild type
DNA; distance from tumor (mm)		 Histopathology; distance from
tumor (mm)
4 8 12 16 4 8 12 16
1 51 M Yes (neo) Yes APC 5 C637T A
1.09
 ND ND ND
Pos
 Neg Neg Neg
B ND ND ND ND Neg Neg Neg Neg
2 47 M Yes (neo) Yes APC 15 C4012T A
0.22
 ND - -
Pos
 Neg - -
B ND ND - - Neg Neg - -
C ND ND ND - Neg Neg Neg -
D ND - - - Neg - - -
3 55 M Yes (neo) Yes KRAS 1 G35A A
0.97
 ND ND -
Pos
 Neg Neg -
B 0.92
 ND ND ND Pos
 Neg Neg Neg
4 59 F Yes (neo) Yes TP53 8 C844T A ND ND ND ND Neg Neg Neg Neg
B ND ND - - Neg Neg - -
5 52 F Yes (neo) Yes KRAS 1 G35T A ND ND ND ND Neg Neg Neg Neg
B ND ND ND ND Neg Neg Neg Neg
6 41 F Yes (neo) Stable APC 6 C646T A ND ND ND ND Neg Neg Neg Neg
B ND ND ND ND Neg Neg Neg Neg
7 63 M Yes (adj) N/A PIK3CA 20 A3140G A ND ND ND ND Neg Neg Neg Neg
B ND ND ND ND Neg Neg Neg Neg
8 69 M Yes (adj) N/A KRAS 1 G35A A ND ND ND ND Neg Neg Neg Neg
B ND ND ND ND Neg Neg Neg Neg
9 64 F Yes (adj) N/A KRAS 1 G35C A ND ND ND ND Neg Neg Neg Neg
B ND ND ND - Neg Neg Neg -
10 53 M Yes (neo) Stable APC 15 4165del TC A ND ND ND ND Neg Neg Neg Neg
B
0.07
 ND ND ND Neg Neg Neg Neg
11 74 M No N/A APC 15 4241-4242 ins T A ND ND ND ND Neg Neg Neg Neg
B ND ND ND ND Neg Neg Neg Neg
12 74 M No N/A APC 15 3927del AAAGA A ND ND ND ND Neg Neg Neg Neg

neo - neoadjuvant chemotherapy

adj - prior adjuvant chemotherapy

samples positive for mutation are outlined

ND - No mutant DNA detected

Neg - Negative