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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Cancer Lett. 2011 Oct 10;316(1):11–22. doi: 10.1016/j.canlet.2011.10.006

Fig. 6.

Fig. 6

A. CTS inhibits the interaction of AR N-terminus and C-terminus using mammalian 2-hybrid interaction assay. B. CTS inhibits the interaction of AR and AR coregulator using mammalian 2-hybrid assay. C. CTS inhibits the E2 and Adiol-induced full-length (flAR) and transactivation. MMTV-Luc reporter was activated through AR in the presence of 10 nM DHT, E2 or Adiol (lanes 2–4). 2.5 µM CTS could effectively inhibit the DHT, E2, and Adiol stimulated AR activity (lanes 6–8). The solvent (EtOH) treated AR-baseline transcriptional activity was counted as 1 fold (lane 1). Data were averaged from three independent experiments.