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. 2011 Sep 30;38(3):119–125. doi: 10.5653/cerm.2011.38.3.119

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Copyright © 2011. The Korean Society for Reproductive Medicine

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Role of dendritic cells (DCs) and macrophages in implantation. Ovarian steroid hormones, E2, and progesterone (P4) stimulate synthesis of growth factors from endometrial epithelial cells, including colony-stimulating factor (CSF-1) and leukemia inhibitor factor (LIF). Uterine DCs are required for efficient decidualization of the endometrium. Macrophages play a largely immune role at this stage (Modified from Pollard JW. J Clin Invest 2008;118:3832-5 [12]). TGF, transforming growth factor; sFLT, soluble FMS-like tyrosine kinase.