Table 1.
Median effective (EC50) and cytotoxic (CC50) concentrations and selective indices (SI) of extracts of PA and TP.
| EC50(µg/ml)1 | CC50(µg/ml)2 | SI3 | ||||
| Extracts | PA | TP | PA | TP | PA | TP |
| Aqueous | 34.9 | >500 | >500 | >500 | nd | nd |
| Ethanol | 31.2 | 121.3 | >500 | >500 | nd | nd |
| Chloroform | 263.9 | >500 | 302.6 | >500 | 1.1 | nd |
| Ethyl acetate | 368.4 | >500 | 389.7 | >500 | 1.1 | nd |
1
50% Antiplasmodial effective concentration.
2
50% Cytotoxic concentration.
3
Selective index. The SI was calculated as the ratio of CC50 to EC50
Data represents means for duplicate experiments.
nd: not determined as a result of determinants being out of range.