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Brg1 mutant spermatocytes arrest at prophase of meiosis I. (A-D) Analysis of meiotic markers, γH2AX or SYCP3, in wild-type (A,C) and Brg1CKO seminiferous tubules (B,D) of 2-week-old testes. Abnormal accumulation of γH2AX- and SYCP3-positive spermatocytes is indicated with block arrow and arrows, respectively (B,D).
