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. 2011 Nov 9;20(3):291–297. doi: 10.1038/ejhg.2011.195

Table 3. Clinical and genetic features of patients with multiple neoplasia including a neuroblastic tumour.

First tumour Second tumour Genetic results
Unilateral retinoblastoma, 16 months Adrenal ganglioneuroblastoma, 9 years ALK, RB1 wt
Unilateral nephroblastoma, 9 months Adrenal neuroblastoma, 9 months No 11p15 LOI, ALK, CDKN1C wt
Neuroblastoma, 3 years Rhabdoid tumour, 22 years ALK wt, SMARCB1 wt
Abdominal NB, 5 years Desmoid tumour, 27 years ALK wt
Melanoma, 22 years Adrenal neuroblastoma, 30 years ALK, CDK4, CDKN2A wt
Neuroblastoma, 9 months Nerve sheath tumour, 28 years ALK wt
Neuroblastoma, 8 years Liposarcoma, 28 years ALK wt
Abdominal neuroblastoma, 3 years Medulloblastoma, 3 years ALK wt

Abbreviations: RB, retinoblastoma; wt, wild type; LOI, loss of imprinting.