Table 2. Mortality (HR) and degree of skewing of X inactivation in all 500 female participants, all above 73 years of age.

Degree of skewing	Min.–Max. value	No. ind.	Adjusted for age			Adjusted for age, cognitive and physical abilities
			HR	95% CI	P-value	HR	95% CI	P-value
First quartile	50–63	131	1 (ref.)	—	—	1 (ref.)	—	—
Second quartile	64–74	121	0.67	0.50–0.92	0.012	0.67	0.48–0.93	0.016
Third quartile	75–87	128	0.87	0.66–1.13	0.29	0.81	0.63–1.05	0.11
Fourth quartile	88 to >95	120	0.77	0.58–1.02	0.065	0.74	0.56–0.98	0.036
Low DS	50–63	131	1.30	1.04–1.64	0.020	1.35	1.08–1.69	0.009
Skewed X inactivation	64 to >95	369	1 (ref.)	—	—	1(ref.)	—	—

Abbreviation: HR, hazard ratio.