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DNA sequence of a part of FGF2 in the affected patients and unaffected individuals. A: A mutation c.866A>C (Gln289Pro) in exon 8 in the affected individuals. B: Sequence of the normal allele of exon 8 subcloned into the pGEM-T vector used as a control. C: A heterozygous missense mutation c.866A>C (Gln289Pro) in exon 8 in the affected individuals. The mutation causes the glutarnine 289 codon (CAG) to change to a proline codon (CCG).
