Table 3. Aqueous cytokine concentrations in PACG and POAG groups.
| POAG (n=26) | PACG (n=12) | ||||||
|---|---|---|---|---|---|---|---|
| Cytokines | Median | Range | Measurable | Median | Range | Measurable | Sensitivity |
| IL-2 | 3.12 | 0–27 | 24/26 | 2.84 | 0–5 | 10/12 | 1.6 |
| IFN-γ | 26.98* | 0–1167 | 24/26 | 27.62 | 13–369 | 12/12 | 6.4 |
| IL-13 | 4.24 | 0–13 | 23/26 | 6.39 | 3–46 | 12/12 | 0.7 |
| IL-17 | 4.15 | 0–151 | 16/26 | 3.30 | 1–241 | 6/12 | 3.3 |
| IL-6 | 2.85 | 0–28 | 16/26 | 4.70 | 2–89 | 11/12 | 2.6 |
| IL-10 | 1.87 | 0–11 | 25/26 | 2.10 | 1–64 | 12/12 | 0.3 |
| IL-12 | 12.42* | 0–68 | 25/26 | 15.90 | 0–32 | 11/12 | 3.5 |
| IL-1β | 0.72 | 0–5 | 23/26 | 0.72 | 0–2 | 10/12 | 0.6 |
| TNF-α | 12.14 | 0–59 | 24/26 | 13.17 | 5–82 | 11/12 | 6.0 |
| IL-1Ra | 8.58 | 0–52 | 18/24 | 14.25 | 3–84 | 9/10 | 5.5 |
| IL-15 | 8.37 | 0–26 | 23/24 | 9.63 | 5–18 | 10/10 | 2.4 |
| IFN-α | 35.10 | 0–311 | 25/26 | 38.25 | 31–128 | 12/12 | 4.3 |
| CCL2 | 287.14 | 0–615 | 25/26 | 325.61 | 145–1072 | 12/12 | 1.1 |
| CCL4 | 31.84 | 1–111 | 25/26 | 36.88 | 12–229 | 12/12 | 2.4 |
| CCL5 | 6.30 | 0–39 | 23/24 | 5.52 | 5–20 | 10/10 | 1.8 |
| CCL11 | 5.30 | 0–17 | 20/24 | 5.89 | 0–10 | 9/10 | 2.5 |
| CXCL8 | 4.88 | 0–42 | 24/26 | 8.00† | 3–81 | 12/12 | 1.0 |
| CXCL9 | 183.43* | 21–1015 | 26/26 | 281.61† | 73–1351 | 12/12 | 1.2 |
| CXCL10 | 116.80 | 0–2311 | 25/26 | 177.39 | 31–4677 | 12/12 | 6.1 |
| IL-7 | 1.88 | 0–3 | 23/26 | 2.06 | 0–4 | 8/12 | 1.1 |
| IL-9 | 7.11 | 0–17 | 23/24 | 8.09 | 5–15 | 10/10 | 2.5 |
| GM-CSF | 151.38 | 0–3139 | 25/26 | 185.12 | 121–6815 | 12/12 | 2.2 |
| PDGF-BB | 2.10 | 0–9 | 9/24 | 2.69 | 1–6 | 5/10 | 2.9 |
| Basic-FGF | 11.39 | 0–34 | 23/24 | 12.16 | 9–35 | 10/10 | 1.9 |
| VEGF | 51.44 | 0–87 | 23/24 | 69.6950 | 27–151 | 10/10 | 3.1 |
*p<0.05, between POAG and cataract; †p<0.05, between PACG and cataract. p-values were obtained from Mann–Whitney U with Bonferroni correction. All concentrations of cytokines are in pg/ml.