Figure 2.

Structural polymorphisms result in gene dosage changes. Top row: haploid gametes with chromosomes represented as colored vertical bars, with wild genotype (wt) and mutated genotype carrying a single translocation (T); middle row: heterozygous diploid individual; bottom row: gametes produced at the next generation, half of which have altered dosage: the translocated segment (red color) is either deleted (Δ), or duplicated (D). Numbers in parentheses indicate the number of copies of the translocated segment.