. 2012 Feb 21;7(2):e30960. doi: 10.1371/journal.pone.0030960

E and monitored for 14 days pi^A.

Virus	Clinical	IHC: No Pos/Total^B ^, ^C		Histopathology: No with Lesions/Total^C				HI
	Disease	Skin	Brain	Skin	Brain	Pancreas	Total	Antibodies
K	0/6^a	0/6^a	0/6^a	1/6^a	0/6^a	0/6^a	1/6^a	5/6
E	3/6^a, ^D	4/6^a	3/6^a	6/6^b	5/6^b	4/6^a	6/6^b	6/6

Birds were euthanized at 14 days pi unless otherwise noted.

IHC = Immunohistochemistry. Positive samples had sparse antigen in the different organs ( = score of 1).

Values within a column with a different superscript minor case letter are significantly different at p<0.05 (two-tailed Fisher's exact test).

Three of the six birds infected with LP VN/1203/E developed ataxia and torticollis and were euthanased, one at 8 days pi and two at 13 days pi.

Table 4. Clinical, pathological and virological responses in chickens inoculated with LP VN/1203/K or LP VN/1203/E and monitored for 14 days piA.