Table 3. Association between ethnic groups and lymph node involvement by tumor size in 3,712 Asian women with breast cancer.a .
Ethnicity | P valueb | |||
Chinese | Malay | Indian | ||
Tumor size less than 20 mm (N = 937) | 0.004 | |||
No nodal involvement, N (%) | 568 (77·0) | 84 (64·6) | 57 (82·6) | |
Lymph node involvement, N (%) | 170 (23·0) | 46 (35·4) | 12 (17·4) | |
Adjusted odds ratio for lymph node involvementc (95% confidence interval) | 1.00 | 1·57 (1·05–2·37) | 0·64 (0·33–1·24) | |
Tumor size 20–50 mm (N = 2,228) | 0.002 | |||
No nodal involvement, N (%) | 865 (53·8) | 160 (43·7) | 125 (49·0) | |
Lymph node involvement, N (%) | 742 (46·2) | 206 (56·3) | 130 (51·0) | |
Adjusted odds ratio for lymph node involvementc (95% confidence interval) | 1.00 | 1·45 (1·15–1·84) | 1·18 (0·89–1·55) | |
Tumor size more than 50 mm (N = 547) | 0.215 | |||
No nodal involvement, N (%) | 105 (30·9) | 34 (25·2) | 16 (2·2) | |
Lymph node involvement, N (%) | 235 (69·1) | 101 (74·8) | 56 (77·8) | |
Adjusted odds ratio for lymph node involvementc (95% confidence interval) | 1.00 | 1·40 (0·88–2·23) | 1·69 (0·92–3·13) |
Only including patients with pathologically confirmed tumor size and lymph node status.
Using Chi Square test.
Logistic regression model adjusted for absolute tumor size (mm), tumor grade, estrogen receptor status, and progesterone receptor status.