Figure 4. Complex of RLX G-quadruplex and berberine.

(A) ESI mass spectrum (100 mM NH₄Ac, pH = 7.0) and (B) CD spectrum (100 mM KCl, 30 mM Tris-HCl, pH = 7.4) for the complex of 10 µM RLX G-quadruplex (G4) and 40 µM berberine at a molar ratio 1∶4.