Table 6. Results of the region-of-interest (ROI)-based analyses of five patients and five age- and gender-matched controls.

ROI	MNI coordinates x/y/z	number of voxels with FA>0.2	average FA	significance level
thalamus patients	(−)11/−21/18	2426±662	0.22±0.04	voxel number: p<0.01average FA: p<0.05
thalamus controls		3113±169	0.26±0.01
upper corticospinal tract patients	(−)22/−21/47	3583±447	0.36±0.07	voxel number: p<0.05average FA: p<0.05
upper corticospinal tract controls		3915±171	0.43±0.04
internal capsule patients	(−)23/−21/15	3347±307	0.37±0.04	voxel number: p<0.001average FA: p<0.001
internal capsule controls		3816±190	0.45±0.03
corpus callosum patients	0/−35/20	2377±519	0.29±0.12	voxel number: p<0.05average FA: p<0.05
corpus callosum controls		3237±239	0.44±0.06

FA values are given as mean ± SD. Significance level was determined by Student's t-test. Left- and right-hemispheric ROIs are arithmetically averaged for each localisation (except from corpus callosum where only one ROI was selected) since there were no asymmetric findings in all of them. MNI, Montreal Neurological Institute; FA, fractional anisotropy.