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. 2012 Feb 21;7(2):e31346. doi: 10.1371/journal.pone.0031346

Table 1. Phenotype of Brg1Wap-Cre mutant mice.

Phenotype
Gender Category Genotype 1 #Litters * Mammary Ovary/Uterus
Male control +/floxed, Tg N/A none N/A
Male control2 null/floxed, Tg N/A none N/A
Male control2 null/floxed, Tg N/A none N/A
Male control2 floxed/floxed, Tg N/A none N/A
Female control floxed/floxed 4 none none3
Female control +/null, Tg 4 none none
Female control +/+, Tg 4 none none
Female control +/+, Tg 4 none none
Female control +/floxed, Tg 2 none none
Female control +/null 4 none none
Female control null/floxed 3 none none
Female control null/floxed 3 none none
Female control null/floxed 3 none none
Female control +/floxed, Tg 3 none none
Female control null/floxed 2 none none
Female control floxed/floxed 2 none none
Female mutant null/floxed, Tg 4 none uterine tumor
Female mutant null/floxed, Tg 4 none ovarian cyst
Female mutant null/floxed, Tg 4 none ovarian cyst, uterine tumor
Female mutant null/floxed, Tg 2 none uterine tumor
Female mutant null/floxed, Tg 3 none ovarian cyst
Female mutant null/floxed, Tg 3 none none
Female mutant floxed/floxed, Tg 4 none none
Female mutant floxed/floxed, Tg 3 none ovarian cyst
Female mutant floxed/floxed, Tg 3 none ovarian cyst, uterine tumor
Female mutant floxed/floxed, Tg 3 none ovarian cyst
Female mutant floxed/floxed, Tg 3 none ovarian cyst
Female mutant null/floxed, Tg 3 none ovarian cyst
Female mutant floxed/floxed, Tg 2 none ovarian cyst
Female mutant floxed/floxed, Tg 3 none ovarian cyst
Female mutant floxed/floxed, Tg 3 none ovarian cyst
Female mutant null/floxed, Tg 3 none ovarian cyst
Female mutant floxed/floxed, Tg 3 none ovarian cyst
Female mutant null/floxed, Tg 2 none ovarian cyst
Female mutant null/floxed, Tg 2 none ovarian cyst
Female mutant null/floxed, Tg 2 none ovarian cyst
Female mutant floxed/floxed, Tg 2 none none

*First pregnancy was at 2–3 months of age, and all mice were analyzed at 15–19 months of age.

1

Tg was hemizygous in each case (Wap-Cre+/0).

2

Mutant genotypically but considered a control because Cre transgene expression is induced by pregnancy, which does not occur in males.

3

Did not score for ovarian or uterine phenotype.